Huo was born in a middle class family in Beijing. Both her parents were dons. She made her debut in an advertisement during 11th grade in school, and entered showbiz as she was invited to participate in a selection test for acting in a television series. After taking the college entrance examination, Huo chose to become a professional actress and started working on some television dramas. Her film debut was My Name Is Fame, in which she co-starred with Hong Kong actor Sean Lau.